What is diaper rash? Diaper rash is a generalized term indicating any skin irritation (regardless of cause) that develops in the diaper-covered region. Synonyms include diaper dermatitis (dermatitis = inflammation of the skin), napkin (or "nappy") dermatitis and ammonia dermatitis. While there are a several broad categories of causes of diaper rash, contact irritation is the most common culprit.
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